Document 0692
 DOCN  M94A0692
 TI    Long term asymptomatic infection in six blood transfusion recipients
       with a single common donor.
 DT    9412
 AU    Learmont J; Tindall B; Sullivan J; Dwyer D; Cunningham A; Wylie B; Red
       Cross Blood Transfusion Service NSW.
 SO    Annu Conf Australas Soc HIV Med. 1993 Oct 28-30;5:35 (abstract no. SC3).
       Unique Identifier : AIDSLINE ASHM5/94348963
 AB    OBJECTIVES: To investigate the possibility of any additional recipients
       from the common donor and to further describe the health status of the
       group. RESULTS: 7 more donations were identified and 4 recipients traced
       and tested. 3 recipients of 1980 donations tested negative. A 77 year
       old female transfused in April 1981 tested anti-HIV positive. She is
       asymptomatic, with conserved CD4+ count, 12 years since transfusion. The
       asymptomatic group have been reviewed an average of 8.5 years following
       infection. They are PCR positive, all remain clinically asymptomatic
       with conserved CD4 counts and none have received anti-viral therapy.
       CONCLUSION: The identification of yet another asymptomatic recipient
       from a single common donor, 12 years since infection, and the continued
       asymptomatic status of the group strongly suggests that the donor and
       the new hosts have all been infected with a relatively non-virulent
       strain of HIV-1.
 DE    Aged  *Blood Donors  *Blood Transfusion  Case Report  Female  Follow-Up
       Studies  Human  HIV Seropositivity/DIAGNOSIS/*TRANSMISSION
       HIV-1/PATHOGENICITY  Leukocyte Count  Polymerase Chain Reaction  T4
       Lymphocytes/IMMUNOLOGY  Virulence  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).